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Higher levels of Vitamin B12 protect against brain changes that happen with aging and less likely to develop dementia and Alzheimers disease

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258 In contrast, the reduction of mitochondrial NAD + levels inhibits SIRT3 activity, increasing ROS levels through the deactivation of superoxide dismutase 2 (SOD2), facilitating the metastasis of hepatocellular carcinoma cells

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Int J Sports Med 28, 633-7 (2007)

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